.animated{-webkit-animation-duration:0.3s;animation-duration:0.3s;-webkit-animation-fill-mode:both;animation-fill-mode:both}.animated.fade-in{-webkit-animation-name:fade-in;animation-name:fade-in}.animated.fade-in-down{-webkit-animation-name:fade-in-down;animation-name:fade-in-down}.animated.fade-out-up{-webkit-animation-name:fade-out-up;animation-name:fade-out-up}.animated.flip{-webkit-backface-visibility:visible;backface-visibility:visible;-webkit-animation-name:flip;animation-name:flip}@-webkit-keyframes fade-in{from{opacity:0}to{opacity:1}}@keyframes fade-in{from{opacity:0}to{opacity:1}}@-webkit-keyframes fade-in-down{from{opacity:0;-webkit-transform:translate3d(0,-100%,0);transform:translate3d(0,-100%,0)}to{opacity:1;-webkit-transform:translate3d(0,0,0);transform:translate3d(0,0,0)}}@keyframes fade-in-down{from{opacity:0;-webkit-transform:translate3d(0,-100%,0);transform:translate3d(0,-100%,0)}to{opacity:1;-webkit-transform:translate3d(0,0,0);transform:translate3d(0,0,0)}}@-webkit-keyframes fade-out-up{from{opacity:1}to{opacity:0;-webkit-transform:translate3d(0,-100%,0);transform:translate3d(0,-100%,0)}}@keyframes fade-out-up{from{opacity:1}to{opacity:0;-webkit-transform:translate3d(0,-100%,0);transform:translate3d(0,-100%,0)}}@-webkit-keyframes flip{from{-webkit-transform:perspective(400px) rotate3d(0,1,0,-360deg);transform:perspective(400px) rotate3d(0,1,0,-360deg);-webkit-animation-timing-function:ease-out;animation-timing-function:ease-out}40%{-webkit-transform:perspective(400px) translate3d(0,0,150px) rotate3d(0,1,0,-190deg);transform:perspective(400px) translate3d(0,0,150px) rotate3d(0,1,0,-190deg);-webkit-animation-timing-function:ease-out;animation-timing-function:ease-out}50%{-webkit-transform:perspective(400px) translate3d(0,0,150px) rotate3d(0,1,0,-170deg);transform:perspective(400px) translate3d(0,0,150px) rotate3d(0,1,0,-170deg);-webkit-animation-timing-function:ease-in;animation-timing-function:ease-in}80%{-webkit-transform:perspective(400px) scale3d(0.95,0.95,0.95);transform:perspective(400px) scale3d(0.95,0.95,0.95);-webkit-animation-timing-function:ease-in;animation-timing-function:ease-in}to{-webkit-transform:perspective(400px);transform:perspective(400px);-webkit-animation-timing-function:ease-in;animation-timing-function:ease-in}}@keyframes flip{from{-webkit-transform:perspective(400px) rotate3d(0,1,0,-360deg);transform:perspective(400px) rotate3d(0,1,0,-360deg);-webkit-animation-timing-function:ease-out;animation-timing-function:ease-out}40%{-webkit-transform:perspective(400px) translate3d(0,0,150px) rotate3d(0,1,0,-190deg);transform:perspective(400px) translate3d(0,0,150px) rotate3d(0,1,0,-190deg);-webkit-animation-timing-function:ease-out;animation-timing-function:ease-out}50%{-webkit-transform:perspective(400px) translate3d(0,0,150px) rotate3d(0,1,0,-170deg);transform:perspective(400px) translate3d(0,0,150px) rotate3d(0,1,0,-170deg);-webkit-animation-timing-function:ease-in;animation-timing-function:ease-in}80%{-webkit-transform:perspective(400px) scale3d(0.95,0.95,0.95);transform:perspective(400px) scale3d(0.95,0.95,0.95);-webkit-animation-timing-function:ease-in;animation-timing-function:ease-in}to{-webkit-transform:perspective(400px);transform:perspective(400px);-webkit-animation-timing-function:ease-in;animation-timing-function:ease-in}}.usa-button,.usa-button-primary,.usa-button:visited,.usa-button-primary:visited,button,select,[type="button"],[type="submit"],[type="reset"],[type="image"]{border-radius:0}.form-field .error-list{padding:0;margin:0;list-style:none;color:#e31c3d;font-size:1.4rem}.form-field .error-list>li{display:list-item;margin:0.4rem 0}.form-field .error-list>li::before,.form-field .error-list>li::after{display:none}.form-field .help-text{color:#757575;margin:0.4rem 0}.inline-dropdown-field{display:inline-block}.inline-dropdown-field>label{display:inline-block;margin:0;cursor:default}.inline-dropdown-field>select{display:inline-block;margin:0;width:auto;height:auto;padding:0 1.5rem 0 0;border:none;background:transparent url("data:image/svg+xml;base64,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") no-repeat right 0 center/1.1rem;font-size:1.4rem}.inline-dropdown-field>select>option{padding-right:0}.inline-dropdown-field .error-list{font-size:1.4rem}.inline-dropdown-field .error-list>li{margin:0}.inline-dropdown-field .help-text{font-size:1.4rem;margin:0}.ncbi-header .agencies .nih{background:transparent url("data:image/svg+xml;base64,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") no-repeat center/cover}.ncbi-header .account .header-button{-webkit-transition:color 0.3s,background-color 0.3s,border-color 0.3s;transition:color 0.3s,background-color 0.3s,border-color 0.3s;margin-right:0;font-size:1.6rem;padding:1rem 2rem;height:3.9rem}@media screen and (max-width:1200px){.ncbi-header .account #account_info{padding:1rem 0.5rem;width:3.9rem;text-align:center}.ncbi-header .account #account_info .username{display:none}}.ncbi-header .account #account_info .fa-user{display:inline-block;width:2rem;height:2rem;margin:-0.5rem 0 -0.4rem;background:url("data:image/svg+xml;base64,PHN2ZyB4bWxucz0iaHR0cDovL3d3dy53My5vcmcvMjAwMC9zdmciIHZpZXdCb3g9IjAgMCAyNCAyNCIgd2lkdGg9IjI0cHgiIGhlaWdodD0iMjRweCI+CiAgPGcgc3R5bGU9ImZpbGw6ICNmZmYiPgogICAgPGVsbGlwc2UgY3g9IjEyIiBjeT0iOCIgcng9IjUiIHJ5PSI2Ii8+CiAgICA8cGF0aCBkPSJNMjEuOCwxOS4xYy0wLjktMS44LTIuNi0zLjMtNC44LTQuMmMtMC42LTAuMi0xLjMtMC4yLTEuOCwwLjFjLTEsMC42LTIsMC45LTMuMiwwLjlzLTIuMi0wLjMtMy4yLTAuOSAgICBDOC4zLDE0LjgsNy42LDE0LjcsNywxNWMtMi4yLDAuOS0zLjksMi40LTQuOCw0LjJDMS41LDIwLjUsMi42LDIyLDQuMSwyMmgxNS44QzIxLjQsMjIsMjIuNSwyMC41LDIxLjgsMTkuMXoiLz4KICA8L2c+Cjwvc3ZnPgo=") no-repeat center/1.6rem}.ncbi-header .account #account_info .sr-only{position:absolute;left:-1000rem;top:-1000rem}.ncbi-header #account_popup{background-color:#ffffff;border:1px solid rgba(0,0,0,0.15);box-shadow:0 3px 1.4rem -0.4rem rgba(0,0,0,0.3);visibility:hidden;opacity:0;-webkit-transition:opacity 0.3s,visibility 0s linear 0.3s;transition:opacity 0.3s,visibility 0s linear 0.3s;display:block}.ncbi-header #account_popup.active{-webkit-transition-delay:0s;transition-delay:0s;visibility:visible;opacity:1}.ncbi-header #account_popup .ncbi-close-button{background:#ffffff url("data:image/svg+xml;base64,PHN2ZyB4bWxucz0iaHR0cDovL3d3dy53My5vcmcvMjAwMC9zdmciIHZpZXdCb3g9IjAgMCA0OCA0OCIgd2lkdGg9IjQ4cHgiIGhlaWdodD0iNDhweCI+CiAgPHBhdGggZD0iTTM4IDEyLjgzbC0yLjgzLTIuODMtMTEuMTcgMTEuMTctMTEuMTctMTEuMTctMi44MyAyLjgzIDExLjE3IDExLjE3LTExLjE3IDExLjE3IDIuODMgMi44MyAxMS4xNy0xMS4xNyAxMS4xNyAxMS4xNyAyLjgzLTIuODMtMTEuMTctMTEuMTd6Ii8+Cjwvc3ZnPgo=") no-repeat center/2.4rem;opacity:.7;-webkit-transition:opacity 0.3s;transition:opacity 0.3s}.ncbi-header #account_popup .ncbi-close-button:hover{opacity:1}.ncbi-footer{border-top-color:rgba(0,0,0,0.15);flex-shrink:0}@media screen and (max-width:599px){.ncbi-footer .usa-grid{padding:0 2rem}}.ncbi-footer .icon-section a,.ncbi-footer .ncbi-section a,.ncbi-footer .gov-agencies a{font-weight:normal}.ncbi-footer h4{font-size:1.8rem}@media screen and (max-width:375px){.ncbi-footer .icon-section .icon-list>li{margin-right:2rem}}@media screen and (max-width:720px){.ncbi-footer .icon-section .icon-list>li:last-child{margin-bottom:0.5em}}@media screen and (max-width:599px){.ncbi-footer .ncbi-section{padding-top:2rem;padding-bottom:2.5rem}}@media screen and (max-width:599px){.ncbi-footer .ncbi-section .ncbi{border-bottom-color:rgba(0,0,0,0.15);margin-left:-2rem;margin-right:-2rem;padding:0 2rem 1.5rem;margin-bottom:2rem}}.ncbi-footer .ncbi-section .ncbi .ncbi-full-name{font-size:2.7rem;line-height:3.9rem}@media screen and (max-width:599px){.ncbi-footer .ncbi-section .ncbi .ncbi-full-name{font-size:2.4rem;line-height:3.2rem}}.ncbi-footer .ncbi-section .ncbi address{font-size:1.8rem;line-height:2.4rem}.ncbi-footer .ncbi-section .ncbi-undecorated-links li{line-height:2rem;margin-bottom:0.8rem}@media screen and (max-width:599px){.ncbi-footer .gov-agencies{padding-top:3rem;border-top-color:rgba(0,0,0,0.15)}}.ncbi-footer #footer_facebook{background:url("../../core/images/ncbi-footer-icons.svg") 0 -0px no-repeat}.ncbi-footer #footer_facebook:hover{background:url("../../core/images/ncbi-footer-icons.svg") 0 -32px no-repeat}.ncbi-footer #footer_twitter{background:url("../../core/images/ncbi-footer-icons.svg") 0 -64px no-repeat}.ncbi-footer #footer_twitter:hover{background:url("../../core/images/ncbi-footer-icons.svg") 0 -96px no-repeat}.ncbi-footer #footer_linkedin{background:url("../../core/images/ncbi-footer-icons.svg") 0 -128px no-repeat}.ncbi-footer #footer_linkedin:hover{background:url("../../core/images/ncbi-footer-icons.svg") 0 -160px no-repeat}.ncbi-footer #footer_youtube{background:url("../../core/images/ncbi-footer-icons.svg") 0 -192px no-repeat}.ncbi-footer #footer_youtube:hover{background:url("../../core/images/ncbi-footer-icons.svg") 0 -224px no-repeat}.ncbi-footer #footer_github{background:url("../../core/images/ncbi-footer-icons.svg") 0 -256px no-repeat}.ncbi-footer #footer_github:hover{background:url("../../core/images/ncbi-footer-icons.svg") 0 -288px no-repeat}@media screen and (min-width:720px){.ncbi-footer #footer_blog{background:url("../../core/images/ncbi-footer-icons.svg") 0 -320px no-repeat}.ncbi-footer #footer_blog:hover{background:url("../../core/images/ncbi-footer-icons.svg") 0 -352px no-repeat}.ncbi-footer #footer_support{background:url("../../core/images/ncbi-footer-icons.svg") 0 -384px no-repeat}.ncbi-footer #footer_support:hover{background:url("../../core/images/ncbi-footer-icons.svg") 0 -416px no-repeat}}.no-script-banner{line-height:2.2rem;padding-top:12px;padding-bottom:12px;background-color:#fff1d2;border-top:1px solid rgba(0,0,0,0.15);border-bottom:1px solid rgba(0,0,0,0.15);color:rgba(0,0,0,0.8);position:relative;z-index:3}.no-script-banner.expanded{box-shadow:0 0 2.5rem rgba(0,0,0,0.3);-webkit-transition:0.3s box-shadow;transition:0.3s box-shadow}.no-script-banner.hidden{height:0;opacity:0;padding:0;border:none;overflow:hidden;-webkit-transition:0.3s height,0.3s opacity,0.3s padding;transition:0.3s height,0.3s opacity,0.3s padding}.no-script-banner a,.no-script-banner a:hover,.no-script-banner a:visited{text-decoration:underline;color:rgba(0,0,0,0.8);display:inline-block}.no-script-banner a:hover{text-decoration:none}.no-script-banner .warning-message{padding-right:8.8rem;padding-left:1rem}@media screen and (min-width:55rem){.no-script-banner .warning-message{padding-left:6.7rem}.no-script-banner .warning-message::before{position:absolute;top:50%;-webkit-transform:translateY(-50%);transform:translateY(-50%);content:'';display:block;width:4.4rem;height:4.4rem;background:url("../../core/images/experiment-icon.svg") no-repeat center/5rem;left:1rem}}.no-script-banner .warning-message a{display:inline-block}.no-script-banner .warning-message .close-banner-button{width:4.4rem;height:4.4rem;overflow:hidden;margin:0;padding:0;position:absolute;top:0.1rem;right:0;outline-offset:-0.3rem;background-color:transparent}.no-script-banner .warning-message .close-banner-button::before{position:absolute;top:50%;-webkit-transform:translateY(-50%);transform:translateY(-50%);content:'';display:block;width:100%;height:100%;background:url("data:image/svg+xml;base64,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") no-repeat center/2.2rem;left:0;-webkit-transform:none;transform:none;margin-top:-50%}.no-session-banner{line-height:2.2rem;padding-top:12px;padding-bottom:12px;background-color:#fff1d2;border-top:1px solid rgba(0,0,0,0.15);border-bottom:1px solid rgba(0,0,0,0.15);color:rgba(0,0,0,0.8);position:relative;z-index:3}.no-session-banner.expanded{box-shadow:0 0 2.5rem rgba(0,0,0,0.3);-webkit-transition:0.3s box-shadow;transition:0.3s box-shadow}.no-session-banner.hidden{height:0;opacity:0;padding:0;border:none;overflow:hidden;-webkit-transition:0.3s height,0.3s opacity,0.3s padding;transition:0.3s height,0.3s opacity,0.3s padding}.no-session-banner a,.no-session-banner a:hover,.no-session-banner a:visited{text-decoration:underline;color:rgba(0,0,0,0.8);display:inline-block}.no-session-banner a:hover{text-decoration:none}.no-session-banner .warning-message{padding-right:8.8rem;padding-left:1rem}@media screen and (min-width:55rem){.no-session-banner .warning-message{padding-left:6.7rem}.no-session-banner .warning-message::before{position:absolute;top:50%;-webkit-transform:translateY(-50%);transform:translateY(-50%);content:'';display:block;width:4.4rem;height:4.4rem;background:url("../../uswds/src/img/alerts/warning.svg") no-repeat center/5rem;left:1rem}}.no-session-banner .warning-message a{display:inline-block}.no-session-banner .warning-message .close-banner-button{width:4.4rem;height:4.4rem;overflow:hidden;margin:0;padding:0;position:absolute;top:0.1rem;right:0;outline-offset:-0.3rem;background-color:transparent}.no-session-banner .warning-message .close-banner-button::before{position:absolute;top:50%;-webkit-transform:translateY(-50%);transform:translateY(-50%);content:'';display:block;width:100%;height:100%;background:url("data:image/svg+xml;base64,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") no-repeat center/2.2rem;left:0;-webkit-transform:none;transform:none;margin-top:-50%}.raw-citation,.full-docsum .docsum-citation{font-size:1.4rem;line-height:2.4rem;color:#4D8055}.full-docsum{padding:0;position:relative;line-height:2.4rem}.full-docsum .docsum-title{display:inline-block;outline-offset:0;word-wrap:break-word;margin:0;font-size:1.8rem;line-height:2.4rem}.full-docsum .docsum-title:focus{box-shadow:0 0 3px #3E94CF,0 0 7px #3E94CF;outline:none;outline:none}.full-docsum .docsum-title b{font-weight:700}.full-docsum .docsum-citation .citation-part{display:inline-block}.full-docsum .docsum-citation .docsum-authors{color:#212121}.full-docsum .docsum-citation .docsum-authors.short-authors{display:inline}.full-docsum .docsum-citation .docsum-journal-citation.short-journal-citation{display:inline}.full-docsum .docsum-citation .free-resources{color:#C05600}.full-docsum .docsum-citation .correction-label{color:#981B1E}@media screen and (min-width:760px){.full-docsum .docsum-citation .free-resources,.full-docsum .docsum-citation .correction-label{font-weight:600}}@media screen and (min-width:760px){.full-docsum .docsum-citation.full-citation .spaced-citation-item{padding-left:2.4rem}.full-docsum .docsum-citation.full-citation>.docsum-authors.short-authors{display:none}.full-docsum .docsum-citation.full-citation>.docsum-authors.full-authors{display:block}.full-docsum .docsum-citation.full-citation>.docsum-journal-citation.short-journal-citation{display:none}.full-docsum .docsum-citation.full-citation>.docsum-journal-citation.full-journal-citation{display:block}}@media screen and (max-width:759px){.full-docsum .docsum-citation.full-citation>.docsum-authors.short-authors{display:inline}.full-docsum .docsum-citation.full-citation>.docsum-authors.full-authors{display:none}.full-docsum .docsum-citation.full-citation>.docsum-journal-citation.short-journal-citation{display:inline}.full-docsum .docsum-citation.full-citation>.docsum-journal-citation.full-journal-citation{display:none}}.full-docsum .docsum-snippet{font-size:1.4rem;line-height:2.4rem}@media print{.full-docsum .docsum-citation .docsum-journal-citation.short-journal-citation,.full-docsum .docsum-citation .docsum-authors.short-authors{display:none}.docsum-journal-citation.full-journal-citation{display:block}}.ncbi-alerts .ncbi-alert__shutdown-outer{position:relative;background-color:#f4e3db;border-left:8px solid #d54309;background-image:url("../../core/images/ncbi-alert-warn.svg")}.ncbi-alerts .ncbi-alert__info-outer{position:relative;background-color:#e7f6f8;border-left:8px solid #00bde3}.ncbi-alerts div[class$="-outer"]{background-position:28px 20px;background-size:32px 32px;background-repeat:no-repeat;padding:20px 20px 20px 28px}.ncbi-alerts div[class$="-inner"]{padding-left:52px;padding-right:52px}@media (max-width:639px){.ncbi-alerts div[class$="outer"]{background-position:25px 15px!important}.ncbi-alerts div[class$="-inner"]{padding-left:0px;padding-right:0px;padding-top:40px}}.ncbi-alerts button.close{cursor:pointer;position:absolute;top:10px;right:20px;width:32px;height:32px;border:0;background-color:transparent;background-image:url("../../core/images/ncbi-alert-close.svg");background-size:32px 32px;background-repeat:no-repeat}.ncbi-alerts button.close:focus{outline:1px dotted #000000}@media (max-width:639px){.ncbi-alerts button.close{right:0px}}.ncbi-alerts p{margin-bottom:0px;margin-top:0px;font-size:18px;line-height:28px}.ncbi-alerts .list-items>p{font-size:0.94em;display:inline}.ncbi-alerts .list-items>p a{font-weight:700}.ncbi-alerts .list-items>p:not(:last-child)::after{margin:0 8px;content:'|'}@media (min-width:768px) and (max-width:991px){.ncbi-alerts .list-items>p:nth-child(2)::after{content:"\a"!important;white-space:pre}}@media (max-width:767px){.ncbi-alerts .list-items>p{display:block}.ncbi-alerts .list-items>p::after{content:""!important}}.dots-loading-indicator{display:none;width:7rem;height:1.8rem;position:relative;-webkit-box-pack:justify;justify-content:space-between;-webkit-box-align:center;align-items:center}.dots-loading-indicator.active{display:-webkit-box;display:flex}.dots-loading-indicator>.dot{width:1.8rem;height:1.8rem;background-color:rgba(0,0,0,0.7);border-radius:100%;-webkit-animation:sk-bouncedelay 1.4s infinite ease-in-out both;animation:sk-bouncedelay 1.4s infinite ease-in-out both}.dots-loading-indicator>.dot-1{-webkit-animation-delay:-0.32s;animation-delay:-0.32s}.dots-loading-indicator>.dot-2{-webkit-animation-delay:-0.16s;animation-delay:-0.16s}@-webkit-keyframes sk-bouncedelay{0%,80%,100%{-webkit-transform:scale(0) rotate(1deg);transform:scale(0) rotate(1deg)}40%{-webkit-transform:scale(1) rotate(1deg);transform:scale(1) rotate(1deg)}}@keyframes sk-bouncedelay{0%,80%,100%{-webkit-transform:scale(0) rotate(1deg);transform:scale(0) rotate(1deg)}40%{-webkit-transform:scale(1) rotate(1deg);transform:scale(1) rotate(1deg)}}.overlay{visibility:hidden;opacity:0;-webkit-transition:opacity 0.2s,visibility 0s linear 0.2s;transition:opacity 0.2s,visibility 0s linear 0.2s;position:fixed;left:0;right:0;top:0;bottom:0;background-color:rgba(0,0,0,0.3);overflow:auto}.overlay .dialog{position:relative;top:50%;left:50%;-webkit-transform:translate(-50%,-50%);transform:translate(-50%,-50%);width:400px;max-width:100%;min-height:30rem;background-color:#ffffff;padding:2rem;-webkit-transition:top 0.5s,-webkit-transform 0.5s;transition:top 0.5s,-webkit-transform 0.5s;transition:transform 0.5s,top 0.5s;transition:transform 0.5s,top 0.5s,-webkit-transform 0.5s}.overlay .dialog .close-overlay{display:block;width:2rem;height:2rem;overflow:hidden;text-indent:-100em;position:absolute;right:2rem;top:2rem;background:url("data:image/svg+xml;base64,PHN2ZyB4bWxucz0iaHR0cDovL3d3dy53My5vcmcvMjAwMC9zdmciIHZpZXdCb3g9IjAgMCA0OCA0OCIgd2lkdGg9IjQ4cHgiIGhlaWdodD0iNDhweCI+CiAgPHBhdGggZD0iTTM4IDEyLjgzbC0yLjgzLTIuODMtMTEuMTcgMTEuMTctMTEuMTctMTEuMTctMi44MyAyLjgzIDExLjE3IDExLjE3LTExLjE3IDExLjE3IDIuODMgMi44MyAxMS4xNy0xMS4xNyAxMS4xNyAxMS4xNyAyLjgzLTIuODMtMTEuMTctMTEuMTd6Ii8+Cjwvc3ZnPgo=") no-repeat center/2.4rem;opacity:.7;margin:0;padding:0}.overlay .dialog .close-overlay:hover{opacity:1}.overlay .dialog>.title{display:block;text-transform:uppercase;font-size:1.9rem;font-weight:300;line-height:2rem;margin-bottom:2rem}.overlay.active{-webkit-transition-delay:0s;transition-delay:0s;visibility:visible;opacity:1;overflow:hidden}body.no-scroll{overflow:hidden}.fake-body-scroll{display:none;position:fixed;right:0;top:0;bottom:0;width:10px;overflow-y:scroll}.dropdown-block{position:relative;display:inline-block}.dropdown-block>.dropdown-container{background-color:#ffffff;border:1px solid rgba(0,0,0,0.15);box-shadow:0 3px 1.4rem -0.4rem rgba(0,0,0,0.3);visibility:hidden;opacity:0;-webkit-transition:opacity 0.3s,visibility 0s linear 0.3s;transition:opacity 0.3s,visibility 0s linear 0.3s;-webkit-transition:opacity 0.3s,visibility 0s linear 0.3s,-webkit-transform 0.3s;transition:opacity 0.3s,visibility 0s linear 0.3s,-webkit-transform 0.3s;transition:opacity 0.3s,transform 0.3s,visibility 0s linear 0.3s;transition:opacity 0.3s,transform 0.3s,visibility 0s linear 0.3s,-webkit-transform 0.3s;position:absolute;z-index:1;-webkit-transform:translate3d(0,-10%,0);transform:translate3d(0,-10%,0);top:100%;left:0}.dropdown-block>.dropdown-container.active{-webkit-transition-delay:0s;transition-delay:0s;visibility:visible;opacity:1;-webkit-transform:translate3d(0,0,0);transform:translate3d(0,0,0)}.notification{padding:0;margin:0;display:block;list-style:none;position:fixed;max-width:31rem;top:50%;left:50%;-webkit-transform:translate(-50%,-50%);transform:translate(-50%,-50%);z-index:1001}.notification>li{display:list-item;margin:0;padding:0}.notification>li::before,.notification>li::after{display:none}.notification .uswdsTheme{padding:2rem;margin-bottom:.5rem;box-shadow:0 2px 2px 0 rgba(0,0,0,0.16),0 0 0 1px rgba(0,0,0,0.08);line-height:2.4rem;font-size:400;color:#212121;border-left:0.4rem solid rgba(0,0,0,0.15)}.notification .uswdsTheme a:visited{color:#0071bc}.notification .uswdsTheme.noty_type__information{border-left-color:#2e8540;background-color:#e7f4e4}.notification .uswdsTheme.noty_type__error{border-left-color:#e31c3d;background-color:#f9dede}.notification .uswdsTheme.noty_type__warning{border-left-color:#fdb81e;background-color:#fff1d2}.notification a.noty-clipboard-link:visited{color:#0071bc}body{display:-webkit-box;display:flex;-webkit-box-orient:vertical;-webkit-box-direction:normal;flex-direction:column;height:100vh}main{-webkit-box-flex:1;flex:1 0 auto}a{text-decoration:none}a:focus{box-shadow:0 0 3px #3E94CF,0 0 7px #3E94CF;outline:none;outline:none}textarea{min-height:4.2rem;min-width:8rem}input[type="checkbox"] + label::before{border-radius:0}@media screen and (min-width:760px){input[type="checkbox"] + label::before{height:1.6rem;width:1.6rem}}.ncbi-base-page-container{margin:0;padding:0;width:auto;max-width:none}.ncbi-header .account{height:3.9rem}.table-sr-only{width:1px;height:1px;overflow:hidden;display:block}*:focus{box-shadow:0 0 3px #3E94CF,0 0 7px #3E94CF;outline:none;outline:none}input[type="radio"]:focus + label::before:focus,input[type="checkbox"]:focus + label::before:focus{box-shadow:0 0 3px #3E94CF,0 0 7px #3E94CF;outline:none;outline:none}input:required:invalid,textarea:invalid{outline:none}*:not(button):not(a):focus{box-shadow:none}option:first-child{font-weight:normal}.usa-button,.usa-button-primary,.usa-button:visited,.usa-button-primary:visited,button,[type="button"],[type="submit"],[type="reset"],[type="image"]{background-color:#20558A}.usa-button:hover,.usa-button-primary:hover,.usa-button:visited:hover,.usa-button-primary:visited:hover,button:hover,[type="button"]:hover,[type="submit"]:hover,[type="reset"]:hover,[type="image"]:hover{background-color:#0071bc}.usa-button:active,.usa-button-primary:active,.usa-button:visited:active,.usa-button-primary:visited:active,button:active,[type="button"]:active,[type="submit"]:active,[type="reset"]:active,[type="image"]:active{background-color:#112e51}@media print{body{display:block;height:auto}.no-script-banner,.ncbi-header,.ncbi-footer{display:none}}